Caveolin induces cardioprotection through epigenetic regulation

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Caveolin induces cardioprotection through epigenetic regulation

Lipid rafts represent a sub-compartment of the plasma membrane that co-ordinate and regulate varieties of signalling processes, whereas caveolins are the integral membrane protein of the lipid raft. Recent evidence demonstrated the pivotal role of caveolins in cardioprotection against ischaemic injury, although their mechanism of action is not clear. However, new understanding of epigenetic mod...

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Integrin regulation of caveolin function

Caveolae are unique organelles that are found in the plasma membrane of many cell types. They participate in various processes such as lipid recycling, cellular signalling and endocytosis. A variety of signalling molecules localize to caveolae in response to various stimuli, providing a potential mechanism for the spatial regulation of signal transduction pathways. Caveolin-1, a constitutive pr...

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ژورنال

عنوان ژورنال: Journal of Cellular and Molecular Medicine

سال: 2012

ISSN: 1582-1838

DOI: 10.1111/j.1582-4934.2011.01372.x